Teaching English is the easiest thing. Lots of work about, but need proper qualifications to make decent money, but if that's not an issue, then you can get (really bad paying) teaching roles.
I've lived, worked, holidayed in Thailand for over 18 years, and if you throw yourself in, there's plenty to do. Happy if you want to share my info with your wife if she has questions. Can't guarantee I'll be able to help, but certainly experienced as a woman 'expat' / traveller πππ½