It will not be easy if she's never traveled outside of Thailand. She has to show that she has a home in Thailand, a good job, money in the bank (over the course of years, not newly deposited money), etc. In other words, she has to show that she will not overstay her visa in the US in search of a green pasture. BUT since you live in Thailand, and hopefully has settled well there with a house and the ability to finance your lifestyle, she can make that a point during the interview. It's worth trying.
girl, I'm rooting for you. Do some indepth research. Go on vacation in Thailand, see how the locals live (don't get tucked into the expat retiree mindset), meet the locals and network. You deserve to explore this dream of yours. Just be prepared.