I'm currently at my Phuket Sandbox hotel, but will move back into my home (on Phuket, mind you) when the nonsensical 14-day hotel stay is over. I see from a few posts back on 5 March that the TM30 is still required. Just checking to ensure that's still the case. I'm on an entirely new visa, so I suppose I have to start the process all over again.
TLDR : Answer Summary
Yes, you need to file a new TM30 at the immigration office when you move out of your hotel and back into your home in Phuket, especially since you are on a new visa.