Can I apply for a re-entry permit while on a non-o visa in Thailand and what are the APEC card entry limitations for my partner?

Hi All, I appreciate any help and advice you can give as answers to several questions I have…

1) I am in Thailand on a non-o visa which expires on 15th Sept. I have funds in Thai account with the intention of applying for 12 month extension for retirement as I am over 50. However, I have an opportunity which may require me to return to my previous country of residence for a few days, can I just apply for a re-entry permit (not sure of the exact terminology), and go a) before I apply for the 12 month extension, or b) after I have applied but before it is granted, or c) must I wait until I have been granted the 12 month extension and the re-entry permit?

2) My partner(not married & under 50) will be joining me entering with an APEC card for the first time, is she limited to 2 land border bounces per year or does the APEC card act as a 5 yr visa so long as you leave every 3 months regardless of whether by land or air?

Thanks for your advice.