This appeared on a Not Everything Else site and typically there was a single response before commenting was closed. The comment was that it was unconfirmed, but, as nobody seems to have tried actually contacting Troy Bakes, I did. He is stuck in Cambodia but I suspect his problems lie elsewhere than reentry being blocked due to time spent in Cambodia.
I have just got back from Chong Chom and I can assure everyone that there is no problem with the standard visa run for the purposres of a valid visa - mine a multiple O based on marriage. In and out in less than 20 minutes. Temperature checks on both sides and a squirt of free gel on the way back into Thailand.
New restrictions coming in from tomorrow for entry into Cambodia mind. Not confirmed as yet .... probably ;-)
TLDR : Answer Summary
A recent discussion highlighted a visa run from Chong Chom to Cambodia for holders of a multiple O visa based on marriage, noting that standard procedures were followed without issues. Temperature checks were conducted upon entry and exit, and the process took less than 20 minutes. However, there are new entry restrictions for Cambodia to be aware of, and differing regulations exist at various borders, such as Poipet, which has specific re-entry requirements.